precisionmedicine相关论文
Thecoronavirusdisease2019(COVID-19)pandemichadadevastatingimpactonhumansociety.Beginningwithgenomesurveillanceofsevereac......
糖尿病是一组病因病理与临床特征高度异质性的疾病。1型糖尿病（T1DM）在遗传学、免疫学、代谢学及治疗学等方面呈现不同的内在型与临......
Cancers of the digestive system(DS),including esophageal,gastric,colorectal,liver,and pancreatic can-cers,have a high in......
胆道外科的历史源远流长。自文艺复兴时期以来，无数前辈从认识胆道开始，由胆囊切除发展到肝外胆管探查，取得显著进步。黄志强院士首次......
Pancreatic cancer is one of the most aggressive malignancies. The poor prognosis of pancreatic cancer patients is mainly......
胰腺癌是致死率极高的恶性肿瘤。历经百余年的发展，胰腺癌的外科治疗技术虽然取得了显著进步，但对患者的生存改善仍差强人意。随着肿......
Identification of Hypertension Subgroups through Topological Analysis of Symptom-Based Patient Simil
Objective:To obtain the subtypes of the clinical hypertension population based on symptoms and to explore the relationsh......
近年来肾癌发病率逐年升高。随着研究的深入，对于肾癌发生发展机制、肿瘤生物学特征有了更多的了解。目前临床常用的肾癌预后判断方......
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Accurate diagnosis of tumors and their pathological states could effectively improve the therapeutic outcomes.Magnetic r......
To diagnosis and treat complicated malignant tumors effectively,multifunctional nanomedicines with targeting,imaging and......
Objective Utilization of next generation sequencing(NGS) to profile tumor sample or biopsy for genetic variations potent......
PU6445 Analysis of clinicopathological features and precision therapy of pseudomyogenic hemangioendo
Objective To investigate the clinicopathological features,misdiagnosis reson and precision therapy to pseudomyogenic hem......
Molecular landscape of gastric cancer patient derived xenograft(PDX)models and its implication in pr
Objective: We aim to catalogue molecular characteristics of gastric cancer PDX models to realize precision medicine and ......
The accurate lymph node dissection for gastric cancer navigated by the preoperative imaging reconstr
Objective To establish the preoperative evaluation system of perigastric vessels and navigate the the precise lymph node......
One important aspect of precision medicine aims to deliver the right medicine to the right patient at the right dose at ......
Business analytics refers to data-driven decision making in business.Nonparametric methods are playing an increasing rol......
This paper addresses dose finding in clinical trials where individuals exhibit biologic characteristics that alter the t......
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Relationship between T-cell receptor α gene polymorphisms and symptomatic differences in patients wi
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Application of Multimodality Imaging Fusion Technology in Diagnosis and Treatment of Malignant Tumor
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糖尿病分型是指导临床决策的重要依据，世界卫生组织(WHO)在1965年首次对糖尿病进行分型，并先后进行了4次更新，这些分型的演变不仅在一......
Delivering safe and effective therapeutic treatment to patients is one of the grand challenges in modern medicine....
Drug safety is one of the key issues in the future realization of precision medicine.However,the molecular basis of ......
Mitochondria are the important organelles that affect tumor initiation,growth,survival,and metastasis.The mitochondr......
Compilation of a minimum set of precise genetic markers with the most predictive effectiveness,multiple functions and di......
多学科协作诊疗(MDT)模式是恶性肿瘤诊疗的发展方向，也是实践精准医学的最好模式。但是，随着医学向数据密集型科学发展，现有的MDT模式......
胃癌在我国的发病率和死亡率均居高不下，免疫治疗有望改善其预后。胃癌分子分型作为胃癌分子诊疗的重要组成内容，是根据基因、免疫微......
抑郁症是一种具有异质性的疾病，抑郁症的异质性主要表现在发病率、发病机制、临床表现、治疗及预后等方面的不同。抑郁的异质性给抑......
精准治疗，是指以个人基因组信息为基础，为患者定制个体化的治疗方案。结直肠癌作为一种高发癌症，手术效果和化疗药物使用均存在着诸多......
随着近年来的肿瘤分子诊断的发展及靶向药物的推广应用，癌症治疗已经逐步进入了精准医学新时代。胃肠间质瘤（gastrointestinal strom......
我国的结直肠癌已经进入高发期。2015年是"精准医学"计划的启动之年。结直肠癌的"精准医学"就是在癌症基因组测序和信息分析基础上......
现代外科学在近30年里的快速发展得益于微创、微创外科、微创医学等概念和理念的提出。作者对“微创”、“微创外科”、“微创医学......
Precision medicine has received growing recognition from clinicians,health systems,and the pharmaceutical industry,as we......
精准用药是未来医疗工作的重要发展方向之一,本文旨在为临床药学专业学生的精准用药教育者提供参考.药物临床疗效的影响因素可分为......
我国结直肠癌发病率及病死率逐年上升，而近年提出的"精准医学"对探究结直肠癌的发生、发展、诊断、治疗、预后评估均有重大意义。在......
采用文献计量学方法,检索1986-2016年ISI Web of Science数据库中精准医学相关文献,分析其发文量、国家/地区、机构、来源出版物等......
Classification of the Gut Microbiota of Patients in Intensive Care Units During Developmentof Sepsis
The gut microbiota of intensive care unit (ICU) patients displays extreme dysbiosis asso-ciated with increased susceptib......
The good and bad sides of exosomes: pre- metastatic niche formation, cancer biomarker and therapy ca
Exosomes, nanovesicles of endocytic origin, are secreted by most cell types; cancer cells representing no exception. Exo......
